2026.04.20
Maximizing the Benefits of NMN: NAD Measurement
Next-Generation Health Investment Through Personalized Preventive Medicine
Over the past three issues, we have explored “Health Investment Strategies for Executives.”
The additive approach to aging care—doing everything said to be beneficial as a precaution—not only yields a low ROI (return on investment), but may also generate hidden costs by depleting the body’s processing capacity (resources). Furthermore, continued excessive investment when cells are already at capacity becomes meaningless under the law of diminishing returns.
The time has come to apply the same “performance measurement” and “optimization” that are standard practice in business and management to your body—your most fundamental capital.
So how should you allocate your limited time and resources to sustain peak performance? In this issue, we propose how to build a personalized “health portfolio” using the NAD measurement service, which will be fully operational at our clinic from May.
A Dashboard for Understanding Your “Current Position”
When building a financial asset portfolio, the first step is to accurately assess your current asset balance. The same principle applies equally to anti-aging care and preventive medicine.
Our clinic’s NAD measurement directly measures blood NAD+ concentration—the key to activating longevity genes (sirtuins) and mitochondria, and to maintaining youthful physical function and clear thinking. The test report visualizes two important data points that clearly indicate your current position.
1. Comparison with peers of the same age (market position)
Your NAD+ value can be objectively assessed in relation to the average for your age group, displayed on a distribution chart ranging from “–” to “++.” If your result is “++” (very high), you can gain the confidence (evidence) that your current health habits and supplement investments are producing excellent results.
2. Changes before and after administration (investment tracking)
By comparing values before and after treatments such as NMN infusions, it is possible to verify whether a given treatment is “genuinely generating returns (ROI) for you at this point in time.” As demonstrated by the director’s data introduced in Part 2, if levels remain unchanged following administration, a clear management decision can be reached: either “the cells are already at capacity and no additional investment is needed,” or “an underlying issue such as inflammation may be present.”

Rebuilding the Portfolio Through “Subtraction” and “Multiplication”
Once your current position (data) is clear, all that remains is to optimize your asset allocation. Based on the data, our physicians will propose the following strategies.
“Subtraction” to eliminate waste
If your NAD+ levels are already sufficiently high, we may recommend reducing the frequency of NMN infusions you have been receiving and redirecting the resulting cost and time savings toward other important areas of care.
“Multiplication” to pursue synergistic effects
When NAD+ levels are plateauing, simply increasing the amount of NMN (addition) is not necessarily the right answer. As supporting components to facilitate the NAD+ metabolic process, we may recommend combining antioxidants such as resveratrol, coenzyme Q10, and 5-ALA.
Combining investment in the surrounding environment (metabolic enzymes) to maximize the core investment (NMN)—this is the medically grounded “multiplication” strategy.
The Optimization Cycle Extends Further “Downstream”
Our clinic’s NAD measurement service will be fully launched in May. We encourage you to use this measurement as your first step toward understanding your current position, eliminating unnecessary investments, and identifying only the care that is truly needed.
However, the advancement of medicine does not end here. There is in fact a deeper reality: “a rise in blood NAD+ concentration does not necessarily mean that cells have been rejuvenated or that physiological activity has been enhanced.”
In business terms, “securing the budget (NAD+)” and “whether the frontline projects (downstream functions) are actually generating results” are separate questions.
Using the NAD+ energy that has been secured, are the “frontline” elements—longevity genes and mitochondria—truly functioning as they should? As the next step in this series, we plan to publish a new column in the near future on “approaches to confirming and measuring whether the functions downstream of NAD+ (the operational status of the frontline) are active.”
Key Takeaways from This Article
- NAD measurement visualizes data such as comparisons with peers of the same age and changes before and after treatment, enabling an accurate understanding of one’s “current position.”
- Based on the data, it becomes possible to not only reduce unnecessary treatments (subtraction) but also to implement a strategy of supporting metabolic efficiency by combining components such as resveratrol (multiplication).
- The next step involves confirming whether NAD+, once produced, is actually functioning within the cells (downstream measurement)—and this is what leads to genuine aging care.
Series Review
Over four issues, we have presented “Health Investment Strategies for Executives.”
- Vol. 1: A health approach based on vague intuition and blind addition is, in business terms, a low-ROI investment made without evidence.
- Vol. 2: Adding costly treatments when cells are already at capacity yields no benefit (the law of diminishing returns). The director’s data illustrates the perspectives of “subtraction” and “the bucket with a hole.”
- Vol. 3: Excessive intake not only wastes resources but generates a “hidden cost” that depletes the body’s processing capacity (resources).
- Vol. 4: The era of optimizing your own “health portfolio” using the fully launched NAD measurement service has arrived.
Thank you sincerely for reading to the end. We hope this series serves as a resource in supporting your continued success and peak performance.
This article is intended to introduce research background and perspectives only and does not indicate any specific effects or efficacy.
Please consult a physician before considering any treatment or use.

