Restore your natural healing capacity — regenerative medicine that supports both wellness and beauty
Our bodies possess an innate ability to repair damage and adapt to changes in the environment. However, aging, stress, and illness can gradually diminish this regenerative capacity. Stem cell conditioned media therapy represents a new approach in advanced regenerative medicine, designed to enhance this intrinsic self-repair mechanism.
Unlike treatments that transplant stem cells directly into the body, this therapy utilizes conditioned media rich in cytokines, growth factors, exosomes, and other bioactive molecules secreted during the stem cell culture process. These factors are believed to play key roles in cellular repair, inflammation control, and the promotion of new blood vessel formation, contributing to overall functional support and anti-aging benefits.
Since the conditioned media does not contain actual cells, it offers a higher safety profile and lower treatment burden compared to stem cell transplantation. Applications range from beauty and skin health to chronic wellness concerns and preventative care, making it a highly anticipated therapy shaping the future of medicine.
At our clinic, we provide stem cell conditioned media therapy under strict scientific and clinical standards, tailoring treatment plans to each individual’s condition and goals. We are committed to helping awaken your body’s natural regenerative power and support a healthier, more vibrant daily life.
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Cytokines
Cytokines are signaling molecules that allow cells to communicate with one another. They act as internal “messengers,” supporting tissue repair, regulating inflammation, and helping coordinate immune function.
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Exosomes
Exosomes are tiny vesicles secreted by cells that carry proteins and genetic material. They function like a biological “delivery system,” transporting information needed for repair and regeneration to other cells.
Potential Benefits of Stem Cell Conditioned Media Therapy
Bioactive substances such as growth factors and cytokines secreted by stem cells may act directly on the body’s own stem cells and regenerative cells, supporting tissue repair and regeneration.
- Support for tissue and nerve repair
- Anti-inflammatory support
- Antioxidant properties
- Support for wound healing
- Immune-modulating effects
- Reduction of oxidative stress
- Support for vascular regeneration and angiogenesis
- Aesthetic and skin-health benefits
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Features of Our Stem Cell Conditioned Media Therapy
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Strict Source Verification and Use of High-Concentration Conditioned Media
At our clinic, the origin of all stem cell conditioned media used for treatment is fully verified and traceable.
We exclusively use products manufactured in certified domestic CPC (Cell Processing Centers), ensuring safety, quality, and complete traceability.
Additionally, we select only formulations supported by data demonstrating significantly higher concentrations of active components compared to other products, offering the potential for more reliable clinical benefit. -
Personalized Treatment Strategy Based on Component Analysis
At our clinic, we directly measure and evaluate the number of exosomes and the concentration of growth factors contained in the conditioned media (such as cytokines, FGF, and VEGF).
Using this data, we tailor the selection of conditioned media type, delivery method, and concentration according to each patient’s treatment goals—whether focused on regeneration, anti-inflammation, skin quality enhancement, or neural repair—enabling a personalized regenerative medicine approach.
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Risks & Side Effects
In rare cases, discomfort at the injection or IV site, minor bleeding, or nerve irritation may occur.
Allergic reactions are considered very uncommon; however, please inform us in advance if you have a history of allergic responses.
Price List
Note: The displayed rates apply to members residing in Japan who hold a health insurance card (My Number Card).
Those without these documents will be charged the non-member rate.
The 3-session course is valid for 3 months.
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Bone marrow–derived conditioned media
1ml 150,150Yen 2ml 300,300Yen 1 vial × 3-session course 330,000Yen -
Umbilical cord–derived conditioned media
1ml 150,150Yen 1 vial × 3-session course 330,000Yen -
Adipose-derived conditioned media
1ml 69,300Yen 5ml 231,000Yen 1 vial × 3-session course 165,000Yen
Medical Expense Deduction
Although stem cell therapy at our clinic is provided as private, non-insured medical care, it may be eligible for Japan’s medical expense tax deduction if it is received for the purpose of treating illness or injury.
Please note that eligibility varies depending on individual circumstances and the judgment of the tax authorities.
For further details, please consult the tax office or a certified tax professional.
Clinical Applications of Stem Cell Conditioned Media
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Intravenous Administration
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(1) Conditioned media is diluted into an IV solution and slowly infused into a vein. The diverse cytokines contained in the conditioned media are believed to activate cells in areas of tissue stress or damage, potentially supporting improvement in age-related functional decline. While this therapy is not intended to treat disease, it may support tissue environments, cellular metabolism, and overall biological resilience, complementing conventional care and wellness strategies.
(2) A key characteristic of stem cell conditioned media is its potential to support repair in areas of tissue need. As weakened cells receive supportive signals, improvements may appear gradually and differ depending on the individual and target tissues. With regular treatment, benefits such as healthy aging support, scalp and hair maintenance, and overall wellness may be expected.
- Cardiovascular function support
- Liver function support
- Respiratory function support
- Kidney function support
- Support for metabolic complications such as diabetes-related conditions
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Intranasal Administration for Brain Delivery
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The active components contained in conditioned media typically cannot cross the blood-brain barrier when administered via standard IV infusion. Therefore, for individuals with neurological conditions or age-related cognitive decline, intranasal delivery is used to support access to the central nervous system.
- Support for memory and cognitive function
- Supportive care for post-stroke neurological symptoms
- Adjunctive support for Parkinson’s disease
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Treatment Frequency
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Response varies from person to person, and some patients may notice benefits after the first session. Many individuals report meaningful results after approximately 5 to 6 treatments.
Stem cell conditioned media can be administered via IV infusion, localized injections, intra-articular injections, or topical application. It is believed to exert therapeutic effects through multiple mechanisms, including growth factors, immunomodulatory signals, anti-inflammatory mediators, and neuroregenerative factors, as well as by supporting activation of the body’s own stem cells.
| Types of Cytokines | Primary Functions |
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| Vascular Endothelial Growth Factor (VEGF) | Hair growth support, follicle stimulation, prevention of capillary rarefaction |
| Epidermal Growth Factor (EGF & family) | Improvement in pigmentation and dullness, enhanced epidermal turnover, reduction in fine lines and wrinkles |
| Keratinocyte Growth Factor (KGF) | Promotes hair growth and follicle regeneration |
| Insulin-Like Growth Factor (IGF) | Skin regeneration, wrinkle reduction, improvement in firmness and elasticity |
| Platelet-Derived Growth Factor (PDGF) | Stimulates cell proliferation and tissue repair/regeneration |
| Transforming Growth Factor (TGF-β, TGF-α family) | Anti-inflammatory effects, wound healing, and cellular regeneration |
| Hepatocyte Growth Factor (HGF) | Supports tissue repair and regenerative activation |
| Ciliary Neurotrophic Factor (CNTF) | Stimulates proliferation and activation of neural stem cells |
| Glial Cell Line-Derived Neurotrophic Factor (GDNF) | Promotes neural cell differentiation and growth, supports dopamine uptake |
| Nerve Growth Factor (NGF) | Supports neurotransmitter synthesis, neuronal survival, repair after injury, cognitive function, and neuroprotection |
| Brain-Derived Neurotrophic Factor (BDNF) | Supports neuronal survival and growth, contributes to cognitive health and dementia prevention |
