2026.03.30
Are NMN supplements and IV therapies actually effective?
Anti-Aging Investment for Executives and “Return on Investment (ROI)”
In daily business operations, executives and business leaders are required to make various investment decisions.
Whether it is launching new ventures, hiring talent, or developing systems, ROI and KPIs (Key Performance Indicators) are typically defined and measured regularly.
This is a fundamental principle in business.
However, how about investment in your most valuable asset—your own health?
“I purchase expensive NMN supplements every month because other executives take them.”
“I regularly undergo trending anti-aging IV therapies as recommended.”
If the effectiveness of such health investments is evaluated only by vague impressions such as “I feel slightly less fatigued” or “I feel better,” it would be considered a high-risk “blind investment” from a business perspective.
Starting from this issue, we will present a four-part column series titled “Health Investment Theory for Executives.”
The Illusion That “Expensive Private Care Equals Effectiveness”
Individuals with a strong interest in advanced preventive medicine and anti-aging care may be particularly prone to a common pitfall: the “addition-based approach.”
“The more high-concentration supplements I take, the greater the anti-aging effect should be.”
“Frequent advanced IV therapies should maximize my performance.”
While advanced compounds such as NMN are being studied for their role in increasing NAD+, a key molecule related to cellular energy and longevity pathways, the human body does not have unlimited absorption capacity.
Each individual has a unique “metabolic capacity limit.”
If high-cost compounds continue to be added when intracellular NAD+ levels are already sufficient (a full container), they may simply be excreted without further benefit.
This may result in a state where valuable resources are wasted, leading to a low ROI.

Visualizing Aging Care KPIs with “NAD Measurement”
Just as business requires accurate assessment of the current situation, managing healthspan also requires measurable indicators (KPIs) to understand one’s physiological status.
Are the anti-aging supplements you are taking suitable for your physiology?
Are the IV therapies you receive truly necessary at the current dosage?
Or have your levels already reached a sufficient range, making additional intake excessive?
Rather than relying on subjective impressions, visualizing these factors through objective data enables optimization by eliminating unnecessary additions. This is the concept of “data-driven personalized medicine (Precision Medicine)” advocated by our clinic.
A key KPI in this context is the level of NAD+, which reflects cellular energy status.
We are introducing “NAD Measurement” as a new solution to accurately evaluate the ROI of your health investments by directly quantifying NAD+ levels in the blood.
This test allows you to determine whether your current supplement and IV strategies are appropriate or excessive based on objective data.
Key Takeaways
- As in business, evaluating ROI is essential in anti-aging and preventive healthcare.
- An “addition-based” approach may result in inefficiency if it exceeds metabolic capacity.
- By using “NAD Measurement”, individuals can quantify their current status and optimize their health strategies.
Summary and Next Topic
This article explained the importance of measuring effectiveness in health investments from a business perspective and introduced NAD measurement as a practical tool.
Moving away from blind additions and toward data-driven optimization is a fundamental principle of next-generation healthcare.
What insights can actually be obtained from NAD measurement, and how should actions be adjusted based on those results?
In the next article, we will revisit the clinic director’s own NAD measurement data—previously discussed—and analyze it from an ROI perspective. We will explore why NAD+ levels did not increase despite high-dose supplementation and additional IV therapy, and what this reveals about truly effective health investment strategies.
This article is intended to introduce research background and perspectives only and does not indicate any specific effects or efficacy.
Please consult a physician before considering any treatment or use.

